2022-present IDG/McGOVERN INSTITUTE FOR BRAIN RESEARCH AT BNU, Director

2022-present State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Professor

2012 - 2022 Professor, Institute of Biophysics, Chinese Academy of Sciences

2009 - 2012 Associate Specialist, and Assistant Professor (Research), UCSF, University of California, at San Francisco

My lab is interested in the function and regulation of neural stem cells in the mammalian brains. More specifically we are working on:
1. Neural stem cell subtypes.
2. Niches and neural differentiation of neural stem cell.
3. Modeling human brain developmental diseases with pluripotent stem cells and in animal models.
4. Cellular mechanism regulating neuronal stem cell fate and circuits formation during the development of cerebral cortex.
5. Molecular regulations of nervous system diseases, including lisencephaly, microcephaly, autism, depression and neurodegenerative diseases.

1. Shi Y, Huang L, Dong H, Yang M, Ding W, Zhou X, Lu T, Liu Z, Zhou X, Wang M, Zeng B, Sun Y, Zhong S, Wang B, Wang W, Yin C, Wang X*, Wu Q Decoding the spatiotemporal regulation of transcription factors during human spinal cord development. Cell Res. 2024 Jan 5. doi: 10.1038/s41422-023-00897-x. Online ahead of print.PMID: 3817724(Cover  Story ). *Corresponding Author

2. Liu M; Wang C; Huo L; Cao J; Mao X; He Z; Hu C; Sun H; Deng W; He W; Chen Y; Gu M; Liao J; Guo N; He X; Wu Q; Chen J; Zhang L; Wang X*; Shang C*; Dong J*.Liu M, Wang C, Huo L, et al. Complexin-1 enhances ultrasound neurotransmission in the mammalian auditory pathway. Nature Genetics, 2024: 1-13. *Corresponding Author

3. Wang W; Yin C; Wen S; Liu Z; Wang B; Zeng B; Sun L; Zhou X; Zhong S; Zhang J; Ma W; Wu Q; Wang X*.DCX knockout ferret reveals a neurogenic mechanism in cortical development. Cell Reports, 2024, 43(8). *Corresponding Author

4. Huo L; Ye Z; Liu M; He Z; Huang M; Li D; Wu Q; Wang Q; Wang X*; Cao P*; Dong J*; Shang C. Brain circuits for retching-like behavior. National Science Review, 2024, 11(1): nwad256. *Corresponding Author

5. Zhong S, Wang M, Huang L, Chen Y, Ge Y, Zhang J, Shi Y, Dong H, Zhou X, Wang B, Lu T, Jing X, Lu Y, Zhang J, Wang X, Wu Q. Single-cell epigenomics and spatiotemporal transcriptomics reveal human cerebellar development. Nat Commun. 2023 Nov 22;14(1):7613. D

6. Yuan B, Wang M, Wu X, Cheng P, Zhang R, Zhang R, Yu S, Zhang J, Du Y, Wang X*, Qiu Z. Identification of de novo Mutations in the Chinese Autism Spectrum Disorder Cohort via Whole-Exome Sequencing Unveils Brain Regions Implicated in Autism. Neurosci Bull. 2023 Oct;39(10):1469-1480. doi: 10.1007/s12264-023-01037-6. Epub 2023 Mar 7.PMID: 36881370 *Corresponding Author

7. Chang S, Wang P, Han Y, Ma Q, Liu Z, Zhong S, Lu Y, Chen R, Sun L, Wu Q, Gao G, Wang X, Chang YZ. Ferrodifferentiation regulates neurodevelopment via ROS generation.  Sci China Life Sci. 2023 Aug;66(8):1841-1857. Doi 10.1007/s11427-022-2297-y. Epub 2023 Mar 14.PMID: 36929272

8. Li A, Liu H, Lei X, He Y, Wu Q, Yan Y, Zhou X, Tian X, Peng Y, Huang S, Li K, Wang M, Sun Y, Yan H, Zhang C, He S, Han R, Wang X*, Liu B. Hierarchical fluctuation shapes a dynamic flow linked to states of consciousness. Nat Commun. 2023 Jun 5;14(1):3238. doi: 10.1038/s41467-023-38972-x.PMID: 37277338 Free PMC article. *Corresponding Author

9. Sun S, Li J, Wang S, Li J, Ren J, Bao Z, Sun L, Ma X, Zheng F, Ma S, Sun L, Wang M, Yu Y, Ma M, Wang Q, Chen Z, Ma H, Wang X, Wu Z, Zhang H, Yan K, Yang Y, Zhang Y, Zhang S, Lei J, Teng ZQ, Liu CM, Bai G, Wang YJ, Li J, Wang X, Zhao G, Jiang T, Belmonte JCI, Qu J, Zhang W, Liu GH. CHIT1-positive microglia drive motor neuron ageing in the primate spinal cord. Nature. 2023 Dec;624(7992):611-620. doi: 10.1038/s41586-023-06783-1. Epub 2023 Oct 31. PMID: 37907096

10. Huo L, Ye Z, Liu M, He Z, Huang M, Li D, Wu Q, Wang Q, Wang X*, Cao P, Dong J, Shang C. Brain circuits for retching-like behavior. Natl Sci Rev. 2023 Sep 27;11 doi: 10.1093/nsr/nwad256. eCollection 2024 Jan.PMID: 38288368 Free PMC article. *Corresponding Author

11. Zeng B, Liu Z, Lu Y, Zhong S, Qin S, Huang L, Zeng Y, Li Z, Dong H, Shi Y, Yang J, Dai Y, Ma Q, Sun L, Bian L, Han D, Chen Y, Qiu X, Wang W, Marín O, Wu Q, Wang Y, Wang X*. The single-cell and spatial transcriptional landscape of human gastrulation and early brain development. Cell Stem Cell. 2023 Jun 1;30(6):851-866.e7. doi: 10.1016/j.stem.2023.04.016. Epub 2023 May 15. (Cover Story).  *Corresponding Author

12.  Wang M, Zhuo L, Ma W, Wu Q, Zhuo Y, Wang X.* AllenDigger, a Tool for Spatial Expression Data Visualization, Spatial Heterogeneity Delineation, and Single-Cell Registration Based on the Allen Brain Atlas. J Phys Chem A. 2023 Mar 30;127(12):2864-2872. doi: 10.1021/acs.jpca.3c00145. Epub 2023 Mar 16. *Corresponding Author

13. 1Jia GX, Ma WJ, Wu ZB, Li S, Zhang XQ, He Z, Wu SX, Tao HP, Fang Y, Song YW, Xu SR, Wang XQ*, Yang QE. Single-cell transcriptomic characterization of sheep conceptus elongation and implantation. Cell Rep. 2023 Aug 29;42(8):112860. doi: 10.1016/j.celrep.2023.112860. Epub 2023 Jul 25.PMID: 37494181. *Corresponding Author

14. Wang J, Yu J, Wang M, Zhang L, Yang K, Du X, Wu J, Wang X, Li F, Qiu Z. Discovery and Validation of Novel Genes in a Large Chinese Autism Spectrum Disorder Cohort. Biol Psychiatry. 2023 Nov 15;94(10):792-803. doi: 10.1016/j.biopsych.2023.06.025. Epub 2023 Jun 29.PMID: 37393044.

15. Yu B, Zhang Q, Lin L, Zhou X, Ma W, Wen S, Li C, Wang W, Wu Q, Wang X*, Li XM. Molecular and cellular evolution of the amygdala across species analyzed by single-nucleus transcriptome profiling. Cell Discov. 2023 Feb 14;9(1):19. doi: 10.1038/s41421-022-00506-y. *Corresponding Author

16. Zhang S, Wu Z, Shi Y, Wang S, Ren J, Yu Z, Huang D, Yan K, He Y, Liu X, Ji Q, Liu B, Liu Z, Qu J, Liu GH, Ci W, Wang X*, Zhang W. FTO stabilizes MIS12 and counteracts senescence. Protein Cell. 2022 Dec;13(12):954-960. doi: 10.1007/s13238-022-00914-6. Epub 2022 Apr 6. *Corresponding Author

17. He L, Yu Z, Geng Z, Huang Z, Zhang C, Dong Y, Gao Y, Wang Y, Chen Q, Sun L, Ma X, Huang B, Wang X, Zhao Y. Structure, gating, and pharmacology of human CaV3.3 channel. Nat Communi. 2022 Apr 19;13(1):2084. doi: 10.1038/s41467-022-29728-0.

18. Yao X , Lu Z, Zhanying Feng, Gao L, Zhou X, Li M, Zhong S, Wu Q, Liu Z, Zhang H, Liu Z,Yi L, Zhou T, Zhao X, Zhang J, Wang Y, Huang X*, Wang X*, Liu J*. Nature Communi. 2022 Jul 6;13(1):3883. doi: 10.1038/s41467-022-31403-3. *Corresponding Author

19. Wang W, Wang M, Yang M, Zeng B, Qiu W, Ma Q, Jing X, Zhang Q, Wang B, Yin C, Zhang J, Ge Y, Lu Y, Ji W, Wu Q*, Ma C*, Wang X*. Transcriptome dynamics of hippocampal neurogenesis in macaques across the lifespan and aged humans. Cell Res. 2022 Jun 24.doi: 10.1038/s41422-022-00678-y. *Corresponding Author

20. Zhou X, Lu Y, Zhao F, Dong J, Ma W, Zhong S, Wang M, Wang B, Zhao Y, Shi Y, Ma Q, Lu T, Zhang J*, Wang X*, Wu Q*. Deciphering the spatial-temporal transcriptional landscape of human hypothalamus development. Cell Stem Cell. 2022 Feb 3;29(2):328-343.e5.

21. Fu, X., He, Q., Tao, Y. Wang. M., Wang W., Wang Y., Yu Q., Zhang F., Zhang X., Chen Y*., Gao D*., Hu P*., Hui L*., Wang X*., and Zeng Y*. Recent advances in tissue stem cells. Sci. China Life Sci. (2021). *Corresponding Author

22. Shi YC, Wang MD, Mi D, Lu T, Wang BS, Dong H, Zhong SJ, Chen YQ,  Sun L, , Wu Q*, Marín O*, Wang X*. Mouse and human share conserved transcriptional programs for interneuron development. Science. 2021, Nov. In press *Corresponding Author

23. Zhou X, Lu YF, Zhao FQ, Dong J, Ma WJ, Zhong SJ, Wang MD,  Wang BS, Zhao YQ, Shi YC, Ma Q, Lu T, Zhang*, Wang X*, Qian Wu* Deciphering the spatial-temporal transcriptional landscape of human hypothalamus development. Cell Stem Cell.  2021.

24. Shi Y, Wu Q, Wang X*. Modeling brain development and diseases with human cerebral organoids. Current Opinion in Neurobiology, 2021, 66: 103-115. *Corresponding Author

25. Ren X, Wen W, Fan X, Hou W, …, Zou B, Zou J, Zuo Z, Bai F, Huang X, Zhou P*, Jiang Q*, Huang Z*, Bei JX*, Wei L*, Bian XW*, Liu X*, Cheng T*, Li X*, Zhao P*, Wang FS*, Wang H*, Su B*, Zhang Z*, Qu K*, Wang X*, Chen J*, Jin R*, Zhang Z*. COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas. Cell, 2021 Apr 1;184(7):1895-1913.e19. *Corresponding Author

26. Ma Y, Xie H, Du X, Wang L, Jin X, Zhang Q, Han Y, Sun S, Wang L, Li X, Zhang C, Wang M, Li C, Xu J, Huang Z, Wang X*, Chai Z, Deng H. In vivo chemical reprogramming of astrocytes into neurons. Cell Discov. 2021 Mar 2;7(1):12. doi: 10.1038/s41421-021-00243-8. *Corresponding Author

27. Xie Z, Wang M, Liu Z, Shang C, Zhang C, Sun L, Gu H, Ran G, Pei Q, Ma Q, Huang M, Zhang J, Lin R, Zhou Y, Zhang J, Zhao M, Luo M, Wu Q*, Cao P*, Wang X* Transcriptomic encoding of sensorimotor transformation in the midbrain. Elife, 2021 Jul 28;10:e69825. doi: 10.7554/eLife.69825. *Corresponding Author

28. Ding W, Zhang C, Wang B, Zhou X, Sun L, Zhong S, Liu J, Zhang J, Wang X*, Wu Q. Loss of the centrosomal protein Cenpj leads to dysfunction of the hypothalamus and obesity in mice. Sci China Life Sci. 2021 Mar;64(3):419-433. doi: 10.1007 *Corresponding Author

29. Fan X, Fu Y, Zhou X, Sun L, Yang M, Wang M, Chen R, Wu Q, Yong J, Dong J, Wen L, Qiao J*, Wang X*, Tang F*. Single-cell transcriptome analysis reveals cell lineage specification in temporal-spatial patterns in human cortical development. Sci Adv. 2020 Aug 21;6(34):eaaz2978. doi: 10.1126/sciadv.aaz2978. *Corresponding Author

30. Xin Zhou, Suijuan Zhong, Honghai Peng, Jing Liu, Wenyu Ding, Le Sun, Qiang Ma, Zeyuan Liu, Ruiguo Chen, Qian Wu, Xiaoqun Wang*. Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus[J]. Nature communications, 2020, 11(1): 1-16. doi: 10.1038/s41467-020-17890-2. *Corresponding Author

31. Shi Y, Wang M, Sun L, Wu Q*, Wang X*. Vascularized human cortical organoids (vOrganoid) model cortical development in vivo" Plos Biology. 2020 May 13;18(5). *Corresponding Author

32. Lu Y, Yi W, Shiau F, Lu S, Wu Q, Xue T, et al Wang X*. Single-cell analysis of human retina identifies evolutionarily conserved and species specific mechanisms controlling development. Developmental Cell. 2020; May 18;53(4):473-491. *Corresponding Author

33. Liu. J, Wang M, Sun L, Pan N, Zhang C, Zhang J, Zuo Z, He S, Wu Q*, Wang X*. Integrative Analysis of in Vivo Recording With Single-Cell RNA-seq Data Reveals Molecular Properties of Light-Sensitive Neurons in Mouse V1. Protein Cell. 2020 Jun; 11(6): 417–432. *Corresponding Author

34. Yin. C, Zhou X, Wang W, Yao Y, Wu Q* and Wang X*. Abundant self-amplifying intermediate progenitors in the subventricular zone of the Chinese tree shrew neocortex. Cereb Cortex, 2020 May 14;30(5):3370-3380 *Corresponding Author

35. Zhong S, Ding W, Sun L, Lu Y, Dong H, Fan X, Liu Z, Chen R, Zhang S, Ma Q, Tang F, Wu Q*, Wang X*. Decoding the development of human hippocampus. Nature, 2020; 577(7791): 531–536. *Corresponding Author

36. Sun L, Chen R, Li L, Yuan B, Song K, Pan N, Chen T, Chang S, Lin K, He X, Wu Q, Xu F, Qiu Z, Wang X*. Visualization and correction of social abnormalities-associated neural ensembles in adult MECP2 duplication mice. Science Bulletin, 2020, 1192–1202 *Corresponding Author

37. Ding W, Zhang C, Wang B, Zhou X, Sun L, Zhong S, Liu J, Zhang J, Wang X*, Wu Q*. Loss of the centrosomal protein Cenpj leads to dysfunction of the hypothalamus and obesity in mice. Sci China Life Sci, 2020: 1-15 Aug 13. doi: 10.1007/s11427-020-1767-5. *Corresponding Author

38. Yi W, Lu Y, Zhong S, Zhang M, Sun L, Dong H, Wang M, Wei M, Xie H, Qu H, Peng R, Hong J, Yao Z, Tong Y, Wang W, Ma Q, Liu Z, Ma Y, Li S, Yin C, Liu J, Ma C, Wang X*, Wu Q*, Xue T*. A single-cell transcriptome atlas of the aging human and macaque retina. National Science Review, 2020 August 25. nwaa179. doi.org/10.1093/nsr/nwaa179 *Corresponding Author

39. Xie H, Zhang W, Zhang M, Akhtar T, Li W, Sun X, Zuo Z, Wei W, Fang X, Yao Z, Dong K, Zhong S, Liu Q, Shen Y, Wu Q, Wang X, Zhao H, Bao J, Qu K, Tian Xue. Chromatin accessibility analysis reveals regulatory dynamics of developing human retina and hiPSC-derived retinal organoids. Sci Adv, 2020; 6(6):eaay5247. Published 2020 Feb 7.

40. Li A, Zalesky A, Yue W, Howes O, Yan H, Liu Y, Fan L, Whitaker KJ, Xu K, Rao G, Li J, Liu S, Wang M, Sun Y, Song M, Li P, Chen J, Chen Y, Wang H, Liu W, Li Z, Yang Y, Guo H, Wan P, Lv L, Lu L, Yan J, Song Y, Wang H, Zhang H, Wu H, Ning Y, Du Y, Cheng Y, Xu J, Xu X, Zhang D, Wang X, Jiang T, Liu B.A. Neuroimaging Biomarker for Striatal Dysfunction in Schizophrenia. Nat Med, 2020 Apr; 26(4):558-565.

41. Yu H, Zhao T, Liu S, Wu Q, Johnson O, Wu Z, Zhuang Z, Shi Y, Peng L, He R, Yang Y, Sun J, Wang X, Xu H, Zeng Z, Zou P, Lei X, Luo W, Li Y. MRGPRX4 is a bile acid receptor for human cholestatic itch. Elife, 2019 Sep 10;8. pii: e48431. doi: 10.7554/eLife.48431.

42. X. Zhang, Z. Liu, X. Liu, S. Wang, Y. Zhang, X. He, S. Sun, S. Ma, N. Shyh-Chang, F. Liu, Q. Wang, X. Wang, L. Liu, W. Zhang, M. Song, G.H. Liu, and J. Qu, Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis. Protein Cell, 2019, 10(9): p. 649-667 DOI: 10.1007/s13238-019-0610-7.

43. Ding W. Y., Wu Q., Sun L, Pan N., and Wang X*. Cenpj regulates cilia disassembly and neurogenesis in the developing mouse cortex. J of Neuroscience. J Neurosci. 2019 Jan 9. *Corresponding Author

44. Yang Y, Chen R, Wu X, Zhao Y, Fan Y, Xiao Z, Han J, Sun L, Wang X, Dai J. Rapid and Efficient Conversion of Human Fibroblasts into Functional Neurons by Small Molecules. Stem Cell Reports, 2019 Nov 12;13(5):862-876. doi: 10.1016/j.stemcr.2019.09.007. Epub 2019 Oct 17.

45. Ji C., Zhao H., Li D., Sun H., Hao J., Chen R., Wang X, H. Zhang, and Y.G. Zhao. Role of Wdr45b in maintaining neural autophagy and cognitive function. Autophagy, 2019: p. 1-11 DOI: 10.1080/15548627.2019.1632621.

46. Pan N, Fang A, Shen C, Sun L, Wu Q and Wang X*. Early Excitatory Activity-dependent Maturation of Somatostatin Interneurons in Cortical Layer 2/3 of Mice Cerebral Cortex, 2019, 29(10) p. 4107-4118 DOI: 10.1093/cercor/bhy293. *Corresponding Author

47. Sun L*, Chen R, Bai Y, Li J, Wu Q*, Shen Q,* Wang X*. Morphological and Physiological Characteristics of Ebf2-EGFP-Expressing Cajal-Retzius Cells in Developing Mouse Neocortex. Cerebral Cortex, 2019. 29(9): p. 3864-3878 DOI: 10.1093/cercor/bhy265. *Corresponding Author

48. D.L. Tong, R.G. Chen, Y.L. Lu, W.K. Li, Y.F. Zhang, J.K. Lin, L.J. He, T. Dang, S.F. Shan, X.H. Xu, Y. Zhang, C. Zhang, Y.S. Du, W.H. Zhou, X. Wang*, and Z. Qiu*, The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice. Neurobiol Dis, 2019. 130: p. 104486 DOI: 10.1016/j.nbd.2019.104486. *Corresponding Author

49. Du R., Zhu X., Wu S., Zhang X., He Y., Zhang K., He X., Wang X., Sun Y., Wang Q., Zhang H., and Tian M., PET imaging of metabolic changes after neural stem cells and GABA progenitor cells transplantation in a rat model of temporal lobe epilepsy. Eur J Nucl Med Mol Imaging, 2019. 46(11): p. 2392-2397 DOI: 10.1007/s00259-019-04408-2.

50. Fan X, Dong J, Zhong S, Wei Y, Wu Q, Yan L, Yong J, Sun L, Wang X, Zhao Y, Wang W, Yan J, Wang X*, Qiao J*, Tang F*. Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysis. Cell Res, 2018 Jul; 28(7):730-745. *Corresponding Author

51. Zhong S, Zhang S, Fan X, Wu Q, Yan L, Dong J, Zhang H, Li L, Sun L, Pan N, Xu X, Tang F*, Zhang J*, Qiao J*, Wang X*. A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex. Nature, 2018 Mar 14.  doi: 10.1038/nature25980. *Corresponding Author

52. Shi Y, Li S, Wu Q, Sun L, Zhang J, Pan N, Wang Q, Bi Y, An J, Lu X, Gao GF*, Wang X*. Vertical Transmission of the Zika Virus Causes Neurological Disorders in Mouse Offspring. Sci Rep, 2018 Feb 23;8(1): 3541. *Corresponding Author.

53. Li R, Sun L, Fang A, Li P, Wu Q*, Wang X*. Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly disease. Protein Cell, 2017 Nov;8(11): 823-833. *Corresponding Author

54. Liu J, Liu W, Yang L, Wu Q, Zhang H, Fang A, Li L, Xu X, Sun L, Zhang J*, Tang F* and Wang X*. Primate-specific gene TMEM14B promotes cortical expansion and folding. Cell Stem Cell, 2017 Nov 2;21(5):635-649. *Corresponding Author

55. Ju XC, Hou QQ, Sheng AL, Wu KY, Zhou Y, Jin Y, Wen T, Yang Z, Wang X, Luo ZG. The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice. Elife, 2016 Aug 9;5.

56. Yuan Q, Deng KY, Sun L, Chi S, Yang Z, Wang J, Xin HB*, Wang X*, Ji G*. Calstabin 2: An important regulator for learning and memory in mice. Sci Rep, 2016 Feb 18; 6: 21087.*Corresponding Author

57. Wang Y, Wu Q, Yang P, Wang C, Liu J, Ding W, Liu W, Bai Y, Yang Y, Wang H, Gao S*, Wang X*. LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain. Nature Communications, 2016 Jan 22; 7:10481. *Corresponding Author

58. Kou Z, Wu Q, Kou X, Yin C, Wang H, Zuo Z, Zhuo Y, Chen A, Gao S*, Wang X*. CRISPR/Cas9-mediated genome engineering of the ferret. Cell Res. 2015 Dec; 25(12): 1372-5. *Corresponding Author

59. Zhao YG, Sun L, Miao G, Ji C, Zhao H, Sun H, Miao L, Yoshii SR, Mizushima N, Wang X, Zhang H. Autophagy, 2015; 11(6): 881-90.

60. Gertz CC, Lui JH, LaMonica BE, Wang X, Kriegstein AR. Diverse behaviors of outer radial glia in developing ferret and human cortex. J Neurosci. 2014 Feb 12;34(7):2559-70.

61. Wu Q, Liu J, Fang A, Li R, Bai Y, Kriegstein AR, Wang X. The dynamics of neuronal migration. Adv Exp Med Biol. 2014; 800:25-36

62. Wang X and Kriegstein. A OSVZ Radial Glial Cells, Book Chapter, Neuroglia. 3^rd Edition. Oxford University Press.

63. Li R, Bai Y, Liu T, Wang X* and Wu Q*. Induced pluripotency and direct reprogramming: a new window for treatment of neurodegenerative diseases. Protein Cell. 2013 Jun; 4(6): 415-24. *Corresponding Author

64. Lamonic B, Liu J, Wang X & Kriegstein A. An updated perspective on human neurodevelopmental disease. Current Opinion in Neurobiology. 2012 Oct; 22(5): 747-53. (Cover)

65. Wu Q* and Wang X*. Neuronal stem cells in the central nervous system and in human diseases. Protein Cell. 2012 Apr; 3(4): 262-70. *Corresponding Author

66. Wang X, Liu J& Kriegstein A. Orienting fate: spatial regulation of neurogenic divisions. Neuron. 2011 Oct. 20; 72(2): 191-3.

67. Wang X*, Tsai JW, LaMonica B, Kriegstein AR. A new subtype of cortical progenitor cell in the mouse embryonic neocortex. Nat Neurosci, 14, 555–561 (2011) (Cover; featured in News and Views)  * Corresponding Author

68. Imai JH, Wang X, Shi SH. Kaede-Centrin1 Labeling of Mother and Daughter Centrosomes in Mammalian Neocortical Neural Progenitors. Curr Protoc Stem Cell Biol. 2010 Oct; Chapter 5: Unit 5.

69. Wang X, Tsai JW, Imai JH, Lian WN, Vallee RB, Shi SH. Asymmetric segregation of mother and daughter centrosome in mammal neocortex. Nature. 2009 Oct 15; 461: 947-55. (Cover; Featured in News and Views).

70. Yu YC, Bultje RS, Wang X, Shi SH. Specific synapses develop preferentially among sister excitatory neurons in the neocortex. Nature 2009 Mar 26; 458: 501-4.

71. Wang X, Yang N, Uno E, Roeder RG, Guo S. A subunit of the mediator complex regulates vertebrate neuronal development. Proc Natl Acad Sci U S A. 2006 Nov 14; 103 (46): 17284-9.