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讲座信息

讲座:Prof.David Hansel,Université Paris Descartes

    邢大军老师课题组邀请了法国Université Paris Descartes的David Hansel教授到实验室做学术报告,欢迎感兴趣的老师和同学参加!以下为报告信息:
    题目:From Physics to Function
    时间:2:00PM, June 15th,2015
    地点:脑成像中心308会议室(大会议室)
    报告人:David Hansel
           "Cerebral Dynamics, Learning and Memory" group
            Center for Neurophysics, Physiology and Pathologies CNRS-UMR8119
            Université Paris Descartes, 45 Rue des Saints Pères , Paris, France
    报告摘要:Strong temporal irregularity and right-skewed, long-tailed distributions of firing rates are distinctive features of cortical spiking activity. Both features are quite puzzling upon consideration of the large number of synaptic inputs a cortical cell receives and the weak correlations among these inputs. A minimal theoretical framework accounting naturally for these features – the balance hypothesis – was proposed by van Vreeswijk and Sompolinsky in two seminal papers at the end of the 1990s. In fact, we showed recently that log-normal distributions of mean firing rates as reported in cortex in-vivo, emerge naturally in the balanced regime. I will summarize the physics and the general phenomenology of the balanced regime as well as their functional consequences for the selectivity of neuronal responses in primary visual cortex. I will address two limitations of the balance hypothesis in its “standard” formulation: 1) it precludes the multi-stability which has been argued to underly the persistent activity of during the retention period of delayed-response tasks 2) it does not account for temporal fluctuations observed in the neuronal activity on time scales on the order of 100 ms-1s as observed in cortex. I will briefly describe possible solutions to these limitations.