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研究团队

PI

李 武Ph.D.   实验室主任

视觉图像解析的脑机制

联系方式

邮箱:liwu#bnu.edu.cn

教育经历

1989.09-1994.06 中国科学院上海生理研究所,神经生物学专业,博士


1984.09-1989.06 中国科学技术大学,生物物理学专业,学士

工作经历

2012.08-现在 北京师范大学IDG/麦戈文脑科学研究院,院长


2011.12-现在 北京师范大学认知神经科学与学习国家重点实验室,主任


2007.06-现在 北京师范大学认知神经科学与学习国家重点实验室,教授


1999.06-2007.06 美国 Rockefeller 大学,研究助理教授


1996.07-1999.05 德国 Max-Planck 生物控制论研究所,访问学者


1994.09-1996.06 美国加州大学 Berkeley 分校,博士后

研究概述

在猕猴执行各种视觉任务的过程中,记录和解码不同脑区神经元的活动,研究多层级、多线程、跨系统的神经信息加工和交互过程,重点关注以下问题:(1)局部图像信息如何在多层级视皮层环路中进行整合和分割,从而形成我们对全局图形的感知;(2)由前额叶和杏仁核等脑区介导的认知和情绪因素如何动态调控视皮层神经元的反应特性,从而有效提取图象中与行为密切相关的信息;(3)学习训练如何优化神经编码和解码过程,从而提高个体的视觉感知分辨能力。

发表文章

1. Jing, R., Yang, C., Huang, X., and Li, W. (2021). Perceptual learning as a result of concerted changes in prefrontal and visual cortex. Current Biology.

2. Zhang, E., and Li, W. (2020). Improved fidelity of orientation perception: a learning effect dissociable from enhanced discriminability. Scientific Reports 10, 6572.

3. Li, Z., Yan, A., Guo, K., and Li, W. (2019). Fear-related signals in the primary visual cortex. Current Biology 29, 4078-4083.

4. Guo, K., Li, Z., Yan, Y., and Li, W. (2019). Viewing heterospecific facial expressions: an eye-tracking study of human and monkey viewers. Experimental Brain Research 237, 2045-2059.

5. Gong, X.J., Li, W., and Liang, H.L. (2019). Spike-field Granger causality for hybrid neural data analysis. Journal of Neurophysiology 122, 809-822.

6. Damon, F., Li, Z., Yan, Y., Li, W., Guo, K., Quinn, P.C., Pascalis, O., and Méary, D. (2019). Preference for attractive faces is species-specific. Journal of Comparative Psychology 133, 262-271.

7. Yan, Y., Zhaoping, L., and Li, W. (2018). Bottom-up saliency and top-down learning in the primary visual cortex of monkeys. Proceedings of the National Academy of Sciences of the United States of America 115, 10499-10504.

8. Hu, M., Li, W., and Liang, H. (2018). A copula-based granger causality measure for the analysis of neural spike train data. IEEE/ACM Transactions on Computational Biology and Bioinformatics 15, 562-569.

9. Liang, H., Gong, X., Chen, M., Yan, Y., Li, W., and Gilbert, C.D. (2017). Interactions between feedback and lateral connections in the primary visual cortex. Proceedings of the National Academy of Sciences 114, 8637-8642.

10. Li, W., and Gilbert, C.D. (2017). Perceptual learning: Neural mechanisms. In Reference Module in Neuroscience and Biobehavioral Psychology (Elsevier).

11. Kuai, S.G., Li, W., Yu, C., and Kourtzi, Z. (2017). Contour integration over time: Psychophysical and fMRI evidence. Cerebral Cortex 27, 3042-3051.

12. Chen, R., Wang, F., Liang, H., and Li, W. (2017). Synergistic processing of visual contours across cortical layers in V1 and V2. Neuron 96, 1388-1402.

13. Wang, R., Wang, J., Zhang, J.-Y., Xie, X.-Y., Yang, Y.-X., Luo, S.-H., Yu, C., and Li, W. (2016). Perceptual learning at a conceptual level. Journal of Neuroscience 36, 2238-2246.

14. Wang, F., Huang, J., Lv, Y., Ma, X., Yang, B., Wang, E., Du, B., Li, W., and Song, Y. (2016). Predicting perceptual learning from higher-order cortical processing. NeuroImage 124, 682-692.

15. Li, W. (2016). Perceptual learning: Use-dependent cortical plasticity. Annual Review of Vision Science 2, 109-130.

16. Hu, M., Li, M., Li, W., and Liang, H. (2016). Data on copula modeling of mixed discrete and continuous neural time series. Data in Brief 7, 1364-1369.

17. Hu, M., Li, M., Li, W., and Liang, H. (2016). Joint analysis of spikes and local field potentials using copula. NeuroImage 133, 457-467.

18. Yan, Y., Zhang, E., and Li, W. (2015). Neural mechanisms of visual perceptual learning. Chinese Bulletin of Life Sciences 27, 867-875.

19. Wang, F., Chen, M., Yan, Y., Zhaoping, L., and Li, W. (2015). Modulation of neuronal responses by exogenous attention in macaque primary visual cortex. Journal of Neuroscience 35, 13419-13429.

20. Abe, H., McManus, J.N.J., Ramalingam, N., Li, W., Marik, S.A., Meyer zum Alten Borgloh, S., and Gilbert, C.D. (2015). Adult cortical plasticity studied with chronically implanted electrode arrays. Journal of Neuroscience 35, 2778-2790.

21. Yan, Y., Rasch, M.J., Chen, M., Xiang, X., Huang, M., Wu, S., and Li, W. (2014). Perceptual training continuously refines neuronal population codes in primary visual cortex. Nature Neuroscience 17, 1380-1387.

22. Meary, D., Li, Z., Li, W., Guo, K., and Pascalis, O. (2014). Seeing two faces together: preference formation in humans and rhesus macaques. Animal Cognition 17, 1107-1119.

23. Chen, M., Yan, Y., Gong, X., Gilbert, C.D., Liang, H., and Li, W. (2014). Incremental integration of global contours through interplay between visual cortical areas. Neuron 82, 682-694.

24. Zhang, E., Zhang, G.-L., and Li, W. (2013). Spatiotopic perceptual learning mediated by retinotopic processing and attentional remapping. European Journal of Neuroscience 38, 3758-3767.

25. Ramalingam, N., McManus, J.N.J., Li, W., and Gilbert, C.D. (2013). Top-down modulation of lateral interactions in visual cortex. Journal of Neuroscience 33, 1773-1789.

26. Piëch, V., Li, W., Reeke, G.N., and Gilbert, C.D. (2013). Network model of top-down influences on local gain and contextual interactions in visual cortex. Proceedings of the National Academy of Sciences of the United States of America 110, E4108-4117.

27. McFarland, R., Roebuck, H., Yan, Y., Majolo, B., Li, W., and Guo, K. (2013). Social interactions through the eyes of macaques and humans. PLOS One 8, e56437.

28. Li, W., and Gilbert, C.D. (2013). Perceptual learning and plasticity in primary visual cortex. In The New Visual Neurosciences, J.S. Werne, and L.M. Chalupa, eds. (Cambridge: MIT Press), pp. 1001-1012.

29. Gilbert, C.D., and Li, W. (2013). Top-down influences on visual processing. Nature Reviews Neuroscience 14, 350-363.

30. Zhang, E., Zhang, G.-L., and Li, W. (2012). Spatiotopic location specificity of perceptual learning in orientation discrimination. Journal of Vision 12, 1140.

31. Xing, D., Shen, Y., Burns, S., Yeh, C.-I., Shapley, R., and Li, W. (2012). Stochastic generation of gamma-band activity in primary visual cortex of awake and anesthetized monkeys. Journal of Neuroscience 32, 13873-13880.

32. Pan, Y., Chen, M., Yin, J., An, X., Zhang, X., Lu, Y., Gong, H., Li, W., and Wang, W. (2012). Equivalent representation of real and illusory contours in macaque V4. Journal of Neuroscience 32, 6760-6770.

33. Gilbert, C.D., and Li, W. (2012). Adult visual cortical plasticity. Neuron 75, 250-264.

34. McManus, J.N.J., Li, W., and Gilbert, C.D. (2011). Adaptive shape processing in primary visual cortex. Proceedings of the National Academy of Sciences of the United States of America 108, 9739-9746.