2011.09 – 2016.07，北京大学&北京生命科学研究所，博士（生物化学与分子生物学）

2006.09 – 2010.06，南开大学，学士（生物技术）

2024.08 – 至今，北京师范大学认知神经科学与学习国家重点实验室，教授

2021.06 – 至今，北京脑科学与类脑研究所，研究员

2016.07 – 2021.05，美国国立卫生研究院药物滥用研究所，博士后

2010.10 – 2011.08，北京生命科学研究所，技术员

课题组使用大鼠和小鼠作为模式动物，研究关联学习和抉择行为的神经生物学基础。具体来说，我们希望在系统神经科学层面理解大脑如何构建环境中事物之间的联系，并且根据以往的经验和当前的需求，组织、维持、更新和泛化学习得到的关联结构，从而预测即将发生的事件和指导动物的抉择行为。为了研究这些问题，我们综合运用多种大小鼠巴甫洛夫和操作式任务，以及一系列神经科学方法，包括多通道在体电生理、单双光子成像、宽场成像、光遗传学、化学遗传学、神经药理学、统计分析、机器学习和计算建模等。通过对神经元活动的观测、操纵和建模，我们探索前额叶皮层和海马等脑区群体细胞的信息编码和计算原理，以及它们之间如何协同工作，实现复杂和灵活的关联学习、记忆和抉择行为。

*第一作者

#通讯作者

1. Lin, H., & Zhou, J#. Hippocampal and orbitofrontal neurons contribute to complementary aspects of associative structure. Nat Commun, 2024, 15, 5283.

2. Ma, F., Zhang, L., & Zhou, J#. Event-specific and persistent representations for contextual states in orbitofrontal neurons. Curr Biol, 2024, 34(5), 1023-1033.

3. Song, W., Liu, X., Huang, H., Wu, Y., Tang, Z., Wang, J., Ma, F., Zhou, J., & Zhang, M#. A frequency-division transceiver for long-range neural signal recording from multiple subjects. IEEE JSSC, 2024, 59(3), 923-934.

4. Zong, W#., Zhou, J., Gardner, M. P. H., Costa, K. M., Zhang, Z., & Schoenbaum, G#. Schema cell formation in orbitofrontal cortex is suppressed by hippocampal output. bioRxiv, 2023, 539307.

5. Bruch, S#., McClure, P., Zhou, J., Schoenbaum G. & Pereira F#. Validating the representational space of deep reinforcement learning models of behavior with neural data. bioRxiv, 2021, 448556.

6. Zhou, J#., Gardner, M. P., & Schoenbaum, G#. Is the core function of orbitofrontal cortex to signal values or make predictions? Curr Opin Behav Sci, 2021, 41, 1-9.

7. Zhou, J#., Zong, W., Jia, C., Gardner, M.P.H., & Schoenbaum, G#. Prospective representations in rat orbitofrontal ensembles. Behav Neurosci, 2021, 135 (4), 518–527.

8. Zhou, J#., Jia, C., Montesinos-Cartagena, M., Gardner, M.P.H., Zong, W., & Schoenbaum, G#. Evolving schema representations in orbitofrontal ensembles during learning. Nature, 2021, 590, 606–611.

10. Gardner, M#., Sanchez, D., Conroy, J.S., Wikenheiser, A., Zhou, J., & Schoenbaum, G#. Processing in lateral orbitofrontal cortex is required to estimate subjective preference during initial, but not established, economic choice. Neuron, 2020, 108, 1-12.

11. Gardner, M#, Conroy, J., Sanchez, D., Zhou, J., & Schoenbaum, G#. Real-time value integration during economic choice is regulated by orbitofrontal cortex. Curr Biol, 2019, 29(24), 4315-4322.

12. Zhou, J#., Montesinos-Cartagena, M., Wikenheiser, A., Gardner, M., Niv, Y., & Schoenbaum, G#. Complementary task structure representations in hippocampus and orbitofrontal cortex during an odor sequence task. Curr Biol, 2019, 29(20), 3402-3409.

13. Zhou, J#., Gardner, M., Stalnaker, T., Ramus, S., Wikenheiser, A., Niv, Y., & Schoenbaum, G#. Rat orbitofrontal ensemble activity contains multiplexed but dissociable representations of value and task structure in an odor sequence task. Curr Biol, 2019, 29(6), 897-907. (F1000 recommended)

14. Wang, D., Li, Y., Feng, Q., Guo, Q., Zhou, J., & Luo, M#. Learning shapes the aversion and reward responses of lateral habenula neurons. eLife, 2017, 6, e23045.

15. Zhang, J., Tan, L., Ren, Y., Liang, J., Lin, R., Feng, Q., Zhou, J., Hu, F., Ren, J., Wei, C., Yu, T., Zhuang, Y., Bettler, B., Wang, F., & Luo, M#. Presynaptic excitation via GABA B receptors in habenula cholinergic neurons regulates fear memory expression. Cell, 2016, 166(3), 716-728.

16. Li, Y., Zhong, W., Wang, D., Feng, Q., Liu, Z., Zhou, J., Jia, C., Hu, F., Zeng, J., Guo, Q., Fu, L., & Luo, M#. Serotonin neurons in the dorsal raphe nucleus encode reward signals. Nat Commun, 2016, 7.

17. Guo, Q*., Zhou, J*., Feng, Q., Lin, R., Luo Q., Zeng S., Luo, M#., & Fu, L#. Multi-channel fiber photometry for population neuronal activity recording. Biomed Opt Express, 2015, 6(10), 3919-3931.

18. Luo M#., Zhou J., & Liu Z. Reward processing by the dorsal raphe nucleus: 5-HT and beyond. Learn Mem, 2015, 22: 452-460.

19. Zhou, J., Jia, C., Feng, Q., Bao, J., & Luo, M#. Prospective coding of dorsal raphe reward signals by the orbitofrontal cortex. J Neurosci, 2015, 35(6), 2717-2730.

20. Liu, Z*., Zhou, J*., Li, Y., Hu, F., Lu, Y., Ma, M., Feng, Q., Zhang, J., Wang, D., Zeng, J., Bao, J., Kim, J., Chen, Z., Mestikawy, S., & Luo, M#. Dorsal raphe neurons signal reward through 5-HT and glutamate. Neuron, 2014, 81(6), 1360-1374. (F1000 recommended).

21. Zhan, C*#., Zhou, J*., Feng, Q., Zhang, J. E., Lin, S., Bao, J., Wu, P., & Luo, M#. Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively. J Neurosci, 2013, 33(8), 3624-3632. (F1000 recommended).

所有文章列表：https://scholar.google.com/citations?user=ZQD-fmcAAAAJ